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Cajun Salmon with Avocado Lime Sauce

Cajun salmon with avocado lime sauce features fiery Cajun-spiced fillets topped with a smooth, vibrant green avocado-lime drizzle. The salmon gets a deeply golden spice crust by pan-searing, then finishes with creamy avocado sauce and fresh cilantro.
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Prep Time 10 minutes
Cook Time 12 minutes
Total Time 22 minutes
Servings: 4 servings
Course: Dinner
Cuisine: American
Calories: 610
Ingredients Equipment Method Notes

Ingredients
  

Salmon fillets
  • 4 salmon fillets About 6 oz each
Cajun seasoning and oil
  • 2 tbsp Cajun seasoning
  • 1 tbsp olive oil
Avocado Lime Sauce
  • 2 ripe avocados For the sauce base
  • 0.25 cup Greek yogurt Use plain, unsweetened
  • 2 limes Juice of 2 limes
  • 1 clove garlic
  • 2 tbsp cilantro
  • 0.25 tsp salt To taste
  • 0.25 tsp black pepper To taste
  • 2 tbsp water To thin, start with 2 tbsp and add more as needed
Garnish
  • 1 lime wedges
  • 1 fresh cilantro

Equipment

  • 1 cast iron skillet

Method
 

Make the avocado lime sauce
  1. Blend the ripe avocados, Greek yogurt, lime juice, garlic, cilantro, salt, pepper, and water until smooth and creamy, adding more water 1 tablespoon at a time to reach a pourable consistency.
Cook the cajun salmon
  1. Season the salmon fillets generously with Cajun seasoning, pressing lightly so it adheres to the surface.
  2. Heat the olive oil in a skillet over medium-high heat, then sear the salmon for 4–5 minutes per side until cooked through and the spice crust is deeply golden.
Finish and serve
  1. Drizzle the avocado lime sauce over each salmon fillet.
  2. Garnish with lime wedges and fresh cilantro before serving.

Notes

For extra creamy sauce, blend until fully smooth, then thin only as needed so it drizzles without running off the salmon. Store leftover salmon and sauce separately in the refrigerator up to 3 days; the salmon reheats best gently. Freezing is not recommended for the avocado sauce due to texture changes. Dietary swap: use Greek yogurt alternatives like unsweetened dairy-free yogurt to keep it creamy while making it dairy-free.